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Updated: 18 Jul 2025

Top 10 Stress Support Supplements

#1
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Youtheory Ashwagandha - 1,000 mg - Stress Support Supplement - Cortisol Support Supplement - Gluten, Dairy & Soy Free - 60 Vegetarian Capsules

Brand: Youtheory
$16.79 ($0.28 / Coun
⭐ 4.1
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    Ashwagandha Supplement: Youtheory Ashwagandha supports stress management and aerobic performance with 1,000 mg of ashwagandha blend per serving*
  • Adaptogen Supplement: Ashwagandha is described as an "adaptogen" because it helps the body adapt to stressful conditions*
  • Clinically Studied: Features clinically studied KSM-66 Ashwagandha and ginger; supplement helps maintain normal cortisol levels already within a normal range*
  • Stress Supplement: This stress support formula is gluten free, dairy free, and soy free; two capsules daily provide 1,000 mg of high-quality ashwagandha blend*
  • The Youtheory Promise: Everything we do is based on a dedication to build pure and effective supplements to support our mission to inspire wellness in all
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#2
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Pure Encapsulations Adrenal Cortex Supplement – Supplement to Support Cortisol Health, Energy Levels, Stress Moderation, and Gland Function – with Bovine Whole Adrenal & Cortex – 60 Capsules*

Brand: Pure Encapsulations
$20.40 ($0.34 / Coun
⭐ 4.8
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    Adrenal Support: This cortisol health supplement provides nutritional support for healthy adrenal function
  • Cortisol Support: This cortisol supplement supports healthy cortisol levels already within a healthy range; it also supports adrenal health and energy levels
  • Unique Supplement: Adrenal is a supplement designed to provide support to your adrenal glands and gland function as well as stress management
  • Pure Quality: Our supplements are made with premium ingredients sourced from trusted suppliers and guided by nutritional experts, then carefully manufactured and tested to verify potency and purity
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
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#3
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Gaia Herbs Stress Response Supplements - Supports Relaxation - with Rhodiola, Holy Basil, Ashwagandha & More - 30 Vegan Liquid Phyto-Capsules (15 Servings)

Brand: Gaia Herbs
$18.89 ($0.63 / Coun
⭐ 4.1
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    Herbal Relaxation Supplement: Formulated with herbal ingredients that support relaxing feelings and overall wellness
  • Natural Energy Aid: Formulated with adaptogens that support healthy sleep and cognitive function
  • Premium Ingredients: Formulated with Siberian rhodiola, ashwagandha, holy basil, and more for cognitive function support
  • Our Commitment to Quality: We source the best ingredients from all over the world for great quality, focusing on people and purpose and not just profit alone
  • Our Story: Since 1987, our purpose has been to connect people, plants, and the planet to create healing because plants hold the wisdom we need to heal
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#4
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Gaia Herbs Adrenal Health Daily Support - with Ashwagandha, Holy Basil & Schisandra - Herbal Supplement to Help Maintain Healthy Energy & Stress Levels - 120 Vegan Liquid Phyto-Capsules (120 Count)

Brand: Gaia Herbs
$52.64 ($0.44 / Coun
⭐ 4.7
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    Adaptogens Supplement: This herbal supplement helps sustain healthy energy and stress levels
  • Premium Ingredients: Contains ashwagandha, holy basil, Rhodiola & schisandra to help balance stress
  • Supports Adrenal Function: Supporting adrenal glands helps stabilize the body during times of stress
  • Transparent: In a clinical study, healthy participants saw an improvement in overall stress scores and support for restorative sleep.*
  • Our Story: Since 1987, our purpose has been to connect people, plants, and planet to support healing
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#5
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Anxie-T - Stress Relief Supplement - Supports Mood & Mental Focus - Feel Calm and Relaxed - Eases Tension & Nervousness - Ashwagandha, Kava Kava, GABA & L-Theanine - 60 Capsules

Brand: LifeSeasons
$32.99 ($0.55 / Coun
⭐ 5
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    Health Benefits - Anxie-T supports the body’s natural ability to deal with common symptoms of stress, including nervousness and nervous exhaustion, stress-related muscle tension, anxious fearfulness, and stress-related sleep problems.
  • Clinically Tested Ingredients - Crafted with all natural ingredients such as Ashwagandha, Kava kava, L-theanine, and Theobromine that all work together. We even use a neurotransmitter called GABA. Its primary role in the body is thought to be the inhibition of nerve excitability.
  • Effective - Most people experience the relaxing effects of Anxie-T the first day they take it, often within 30 minutes. It usually induces a feeling of calm, and won’t make you feel tired.
  • Day & Night Support - Take three Anxie-T stress support supplements each morning, with or without food. An additional capsule can be added at night to support a good night’s sleep.
  • One Unique Blend - Achieving a change in health requires the right ingredients in the right doses. This used to require purchasing many individual vitamins and nutrients to create an effective blend. LifeSeasons was doctor formulated to put that blend into one bottle.
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#6
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THORNE Adrenal Cortex - Supplement for Cortisol Management - Support Healthy Adrenal Gland Function, Immune System, Stress Management, Fatigue & Metabolism* - 60 Capsules

Brand: THORNE
$19.00 ($0.32 / Coun
⭐ 4.1
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    Support For A High-Stress World: Lifestyle habits that deprive us of adequate rest and exercise, and poor dietary habits can, over time, take their toll on the adrenal glands
  • Adrenal support: Formulated with a unique extract to nourish the adrenal glands, which help regulate metabolism and the body’s stress response*
  • Promote energetic feelings: Helps maintain immune function and promotes an energetic feeling*
  • Stabilize stress hormone: Helps stabilize the stress hormone, cortisol, which naturally peaks in the morning and declines during the day – too much stimulus (stress) can cause cortisol to get out of balance
  • Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
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#7
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OLLY Ultra Strength Goodbye Stress Softgels, GABA, Ashwagandha, L-Theanine and Lemon Balm, Stress Relief Supplement - 60 Count

Brand: OLLY
$18.99 ($0.32 / Coun
⭐ 4.1
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    OLLY ULTRA STRENGTH GOODBYE STRESS ULTRA SOFTGEL: Goodbye Stress Ultra Softgels are blended with powerful botanicals and nutrients to help you stay calm and centered
  • THE GOODS INSIDE: OLLY Goodbye Stress softgels are expertly blended with GABA, a fast working (within 30-60 minutes) active that supports a relaxed state of mind. L-Theanine is GABA's partner in sublime—it goes right to work in your brain to help you keep your cool, and Lemon Balm is a soothing botanical that has been used for centuries to help quiet the mind. Plus Ashwagandha for mood and energy support
  • HOW TO TAKE: Take 2 softgels per day with water as needed. Swallow whole, do not chew. Comes with 60 capsules per bottle for a 30 day supply
  • ULTRA SOFTGELS: Our premium Softgel blends are naturally colored, easy to swallow and have a hint of strawberry scent with zero sugar. This stress aid supplement also come in a convenient compact package.
  • MIX AND MATCH: Delightful OLLY products can be taken together—mix and match as you please
  • MORE OLLY GOODNESS: We create products that are just as effective as they are delicious—gummies, multivitamins, drink powders, premium softgels and more ways to feel happy inside out
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#8
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Integrative Therapeutics - Cortisol Manager - Supplement with Ashwagandha and L-Theanine - Supports Relaxation & Calm* - 30 Tablets

Brand: Integrative Therapeutics
$25.75 ($0.86 / Coun
⭐ 4.2
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    Cortisol Manager: With ongoing use, these certified vegan tablets support balanced cortisol levels and a healthy response to stress*
  • Ashwagandha & L-Theanine Supplement: This stress support supplement contains a blend of Sensoril brand ashwagandha (Withania somnifera) and L-theanine*;Sensoril is a registered trademark of Natreon, Inc.
  • Supports Restful Sleep: This supplement helps support relaxation and calm to support restful sleep*
  • Stress Support: Your adrenal glands play a large role in supporting stress levels; this adrenal support supplement supports stress while supporting adrenal health*
  • For over 35 years, patients and clinicians have trusted Integrative Therapeutics for our dedication to quality, potency, and accuracy; transparency around our sourcing and manufacturing processes is part of our quality promise to you
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#9
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NOW Foods Supplements, Adrenal Stress Support, Cortisol Support Formula* with Relora®, For Typical Everyday Stress*, Appetite Management*, 90 Veg Capsules

Brand: NOW Foods
$18.51 ($0.21 / Coun
⭐ 4.1
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    ADRENAL SUPPORT: A botanical and nutritional blend formulated to naturally support a healthy adrenal stress response
  • APPETITE MANAGEMENT: Combines vitamin C, pantothenic acid, and chromium with Relora to support healthy adrenal function, relieve stress, and promote healthy eating patterns
  • CERTIFICATIONS/CLASSIFICATIONS: Vegan, Nut Free, Made without Gluten, Dairy Free, Egg Free, Kosher
  • Appetite Management
  • A Dietary Supplement
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#10
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Nature's Bounty Stress Relief Ashwagandha KSM 66 Tablets, Mood Support, 50 Count

Brand: Nature's Bounty
$9.33 ($0.19 / Count
⭐ 4.7
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    PLANT-BASED STRESS RELIEF: Unlike some other stress supplements Nature’s Bounty Stress Relief tablets use plant-based ingredients to support a calm state of mind and help you manage occasional stress (1)
  • SUPPORT FROM ASHWAGANDHA: Nature’s Bounty Stress Relief tablets contain 600 mg Ashwagandha KSM-66 per serving; Ashwagandha KSM-66 is a clinically studied herbal extract that supports a healthy response to occasional stress (1)
  • WITH L-THIANINE: Each serving of Nature’s Bounty Stress Relief contains 200mg of the amino acid L-Theanine to support the mood centers of the brain and promote a calm and relaxed mental state (1)
  • QUALITY IS OUR PRIORITY: Nature’s Bounty is committed to the safety of our supplements; Our Stress Relief tablets are non-GMO; gluten free; sugar free; and contain no artificial color; flavor; or sweetener
  • FROM THE TRUSTED WELLNESS EXPERTS: Nature’s Bounty Anxiety & Stress Relief tablets are a product of nearly 50 years of dedication to quality; consistency; and scientific research to make vitamins and nutritional supplements of excellence
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